The accessibility standards of Section 508 of the Rehabilitation Act can be challenging to implement for an instructional designers as they need to address every element on the screen like alt-text, tabbing, transcript, colour contrast, etc.
Articulate Storyline 360 supports Section 508 accessibility standards which includes:
JAWS readers
Full keyboard navigation
Visible focus indicator
Video subtitle (using timed text boxes)
Slide transcripts using Notes tab
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